If someone wants to take psyllium husks to help maintain regularity, they can be taken either between meals or with meals, whichever is most comfortable. If someone wants to take psyllium husks to help maintain cholesterol levels within the normal range and support heart health, they will be slightly more effective when taken with meals. Psyllium husks do not interfere with the absorption of vitamins, minerals and other nutrients when taken as directed, either with meals or between meals.
The reason why has to do with how psyllium husks work in the body. Psyllium husks swell when mixed with liquid and create added bulk that is beneficial for the digestive system. The key is that the added bulk has different effects in the small intestine and the colon.
In the small intestine, when psyllium husks are taken with food, the added bulk results in the food moving more slowly through the small intestine. This gives more time for the digestive enzymes in the small intestine to pull vitamins, minerals and other nutrients out of the food, and for the nutrients to be absorbed into the bloodstream. As a result, there is not a problem of interference with nutrient absorption. This slower absorption provides the additional health benefit that sugar and simple carbohydrates from meals are absorbed more slowly in the small intestine, reducing the ups and downs of blood sugar spikes, and reducing between-meal hunger pangs..
In the colon, the added bulk from psyllium husks helps to promote regularity and pushes waste material slightly faster through the colon. This is beneficial, as the body gets rid of its wastes and toxins more thoroughly and quickly when psyllium husks are taken.